Route 64/66 Western Lights Centro's Route 64/66 schedule is divided into two distinct routes: Route 64 Western Lights & Route 66 Grand Ave.

Route 64 provides direct service connecting downtown Syracuse and the near west side with Western Lights, Wegmans and St. Bellevue Manor via West Onondaga St. and Onondaga Blvd. This route also provides continuing service beyond downtown Syracuse to Shoppingtown as a Centro Route 68.

Route 66 provides direct service connecting downtown Syracuse and the near west side with Western Lights, Wegmans and St. Camillus via Delaware St. and Grand Ave. This route also provides continuing service beyond downtown Syracuse to Shoppingtown as a Centro Route 68.